In Vitro and In Vivo Effects of the Urokinase Plasminogen Activator Inhibitor WX-340 on Anaplastic Thyroid Cancer Cell Lines

In Vitro and In Vivo Effects of the Urokinase Plasminogen Activator Inhibitor WX-340 on Anaplastic Thyroid Cancer Cell Lines

Increased expression of the urokinase-type plasminogen activator (uPA) system is associated with tumor invasion, neo-angiogenesis, and metastatic spread, and has been shown to positively correlate with a poor prognosis in several cancer types, including thyroid carcinomas. In recent years, several u...

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Bibliographic Details
Main Authors: Enke Baldini, Dario Presutti, Pasqualino Favoriti, Simonetta Santini, Giuliana Papoff, Chiara Tuccilli, Raffaella Carletti, Cira Di Gioia, Eleonora Lori, Iulia Catalina Ferent, Federica Gagliardi, Antonio Catania, Daniele Pironi, Domenico Tripodi, Vito D’Andrea, Salvatore Sorrenti, Giovina Ruberti, Salvatore Ulisse
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
anaplastic thyroid cancer
urokinase plasminogen activator
WX-340
xenograft
proliferation
cell adhesion
Online Access:https://www.mdpi.com/1422-0067/23/7/3724

Internet

https://www.mdpi.com/1422-0067/23/7/3724

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