Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes

Background: Dormant ribosomes are typically associated with preservation factors to protect themselves from degradation under stress conditions. Stm1/SERBP1 is one such protein that anchors the 40S and 60S subunits together. Several proteins and tRNAs bind to this complex as well, yet the molecular...

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Bibliographic Details
Main Authors: Mengtan Du, Xin Li, Wanlin Dong, Fuxing Zeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1395220/full