Circular RNA circVAMP3 promotes aerobic glycolysis and proliferation by regulating LDHA in renal cell carcinoma

Abstract Metabolic dysfunction is seen in cancer cells where increased glycolysis provides energy for growth. Circular RNAs (circRNAs) are thought to assist in glucose metabolism and the switch to glycolysis. Through screening, we found that circVAMP3 was necessary for both glycolytic and proliferat...

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Bibliographic Details
Main Authors: Jun Li, Qian Zhang, Yupeng Guan, Dingzhun Liao, Donggen Jiang, Haiyun Xiong, Hengji Zhan, Jun Pang
Format: Article
Language:English
Published: Nature Publishing Group 2022-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04863-0