Myosin-independent stiffness sensing by fibroblasts is regulated by the viscoelasticity of flowing actin
Abstract The stiffness of the extracellular matrix induces differential tension within integrin-based adhesions, triggering differential mechanoresponses. However, it has been unclear if the stiffness-dependent differential tension is induced solely by myosin activity. Here, we report that in the ab...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-01-01
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Series: | Communications Materials |
Online Access: | https://doi.org/10.1038/s43246-024-00444-0 |