JAK2 gene knockout inhibits corneal allograft rejection in mice by regulating dendritic cell-induced T cell immune tolerance

Abstract Corneal allograft rejection can be seen in some patients after corneal transplantation. The present study intends to investigate whether JAK2 gene knockout affects corneal allograft rejection through regulation of dendritic cells (DCs)-induced T cell immune tolerance. In order to identify t...

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Bibliographic Details
Main Authors: Jun Hu, Wanping Zhang, Lingjuan Xu, Lihua Hu
Format: Article
Language:English
Published: Nature Publishing Group 2022-06-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-01067-5