TRADD regulates perinatal development and adulthood survival in mice lacking RIPK1 and RIPK3
Programmed cell death regulates early development but how various factors (for example, TRADD, FADD and RIPKs) regulate this is unclear. Here, the authors show that a single allele of Tradd is essential for survival, when both Ripk3 and Ripk1 are knocked out in mice, and RIPK1 protects thymocytes fr...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2019-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-08584-5 |