Evaluation of cyclophosphamide-induced genotoxicity and cytotoxicity in cultured human lymphocytes

Evaluation of cyclophosphamide-induced genotoxicity and cytotoxicity in cultured human lymphocytes

Aim: The present study was aimed to examine and evaluate the genotoxicity and cytotoxicity induced by different doses of cyclophosphamide (CP) in normal healthy cultured human peripheral blood lymphocytes. Materials and Methods: Genotoxicity and cytotoxicity was evaluated through mitotic index (MI)...

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Bibliographic Details
Main Authors: Ravindra M Samarth, Tooba Khan, Shweta Srivas, Pradyumna K Mishra, Rajnarayan R Tiwari
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Journal of Radiation and Cancer Research
Subjects:
Chromosomal aberrations
colony formation assay
cyclophosphamide
human peripheral blood lymphocytes
micronuclei frequency
Online Access:http://www.journalrcr.org/article.asp?issn=0973-0168;year=2018;volume=9;issue=1;spage=28;epage=32;aulast=Samarth

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http://www.journalrcr.org/article.asp?issn=0973-0168;year=2018;volume=9;issue=1;spage=28;epage=32;aulast=Samarth

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