Evaluation of cyclophosphamide-induced genotoxicity and cytotoxicity in cultured human lymphocytes

Evaluation of cyclophosphamide-induced genotoxicity and cytotoxicity in cultured human lymphocytes

Aim: The present study was aimed to examine and evaluate the genotoxicity and cytotoxicity induced by different doses of cyclophosphamide (CP) in normal healthy cultured human peripheral blood lymphocytes. Materials and Methods: Genotoxicity and cytotoxicity was evaluated through mitotic index (MI)...

Full description

Bibliographic Details
Main Authors:	Ravindra M Samarth, Tooba Khan, Shweta Srivas, Pradyumna K Mishra, Rajnarayan R Tiwari
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2018-01-01
Series:	Journal of Radiation and Cancer Research
Subjects:	Chromosomal aberrations colony formation assay cyclophosphamide human peripheral blood lymphocytes micronuclei frequency
Online Access:	http://www.journalrcr.org/article.asp?issn=0973-0168;year=2018;volume=9;issue=1;spage=28;epage=32;aulast=Samarth

Similar Items

CHROMOSOMAL ABERRATIONS AND MICRONUCLEI IN LYMPHOCYTES OF MEDICAL RADIATION WORKERS EXPOSED TO LONIZING RADIATION BELOW DOSE LIMIT
by: MOZDARANI H, et al.
Published: (2001-01-01)

IN VITRO ANALYSIS OF TARTRAZINE GENOTOXICITY AND CYTOTOXICITY
by: Anja Haverić, et al.
Published: (2017-06-01)

In Vivo Genotoxicity of Gold Nanorods in Mouse Bone Marrow Compared with Cyclophosphamide
by: Amira M. Gamal-Eldeen, et al.
Published: (2016-12-01)

by: S. Christobher, et al.
Published: (2017-04-01)

Effects of melatonin on DNA damage induced by cyclophosphamide in rats
by: S.G. Ferreira, et al.
Published: (2013-03-01)

Effects of melatonin on DNA damage induced by cyclophosphamide in rats
by: S.G. Ferreira, et al.
Published: (2013-08-01)

Waste anesthetic gases have a significant association with deoxyribonucleic acid (DNA) damage: A systematic review and meta-analysis of 2,732 participants
by: Mayang Indah Lestari, et al.
Published: (2023-09-01)

DNA DAMAGE IN MINERS (LITERATURE REVIEW)
by: Yu. E. Kulemin, et al.
Published: (2014-09-01)

Genotoxic and cytotoxic effect of mirtazapine in human peripheral blood lymphocyte: in vitro study
by: Norizadeh Tazehkand M, et al.
Published: (2015-06-01)

Lymphocyte chromosomal aberration assay in radiation biodosimetry
by: Paban K Agrawala, et al.
Published: (2010-01-01)

Effects of Flaxseed (Linum Usitatissimum L.) against Genotoxicity Induced by Cyclophosphamide on Human Blood Lymphocyte
by: Mohammad Shokrzadeh, et al.
Published: (2019-06-01)

Cytotoxic and Immunetoxic Associated with Occupational Chemical Exposure, Baghdad, Iraq
by: Azhar M Haleem, et al.
Published: (2019-12-01)

Cytotoxic and Immunetoxic Associated with Occupational Chemical Exposure, Baghdad, Iraq
by: Azhar M Haleem, et al.
Published: (2019-12-01)

Cytotoxicity and genotoxicity of low doses of mercury chloride and methylmercury chloride on human lymphocytes in vitro
by: L.C. Silva-Pereira, et al.
Published: (2005-06-01)

Genotoxic Effects and Liver Toxicity in Swiss Albino Mice Males after Acute and Chronic Exposure of Diacetyl and Butter flavors
by: Mohamed AboelMaaty, et al.
Published: (2021-08-01)

Genotoxicity of titanium dioxide nanoparticles and triggering of defense mechanisms in Allium cepa
by: Ronaldo dos Santos Filho, et al.

Genotoxic and cytotoxic evaluation of venlafaxine in an acute and a subchronic assay in mouse
by: E. Madrigal-Bujaidar, et al.
Published: (2021-12-01)

Cytotoxic, clastogenic and genotoxic effects of cis-tetraammine(oxalato)ruthenium(III) dithionate on human peripheral blood lymphocytes
by: Manuela da Rocha Matos Rezende, et al.
Published: (2020-05-01)

In vitro analysis of thimerosal genotoxicity and cytotoxicity effect
by: Mirela Mačkić-Đurović, et al.
Published: (2022-03-01)

Allium test genotoxicity data on water from river valley of Irtysh, West Siberia
by: Dmitry S. Pesnya, et al.
Published: (2022-04-01)

INFLUENCE OF BASIC VARIABLES ON MICRONUCLEI FREQUENCY AND CHROMOSOMAL ABERRATIONS IN GENERAL POPULATION OF FB&H
by: Mirela Mačkić-Đurović, et al.
Published: (2017-06-01)

<i>Rosa damascena</i> Mill. Essential Oil: Analysis of In Vitro and In Vivo Genotoxic and Cytotoxic Potentials by Employing Three Cytogenetic Endpoints
by: Tsvetelina Gerasimova, et al.
Published: (2024-12-01)

Genotoxic potential of a novel PDE-4B inhibitor Apremilast by chromosomal aberration and micronucleus assay in mice
by: Muhammad Afzal, et al.
Published: (2020-05-01)

Research on Spontaneously Emerged Chromosomal Aberrations in the Periphery Blood Lymphocytes in Cattle (‘Buša’ Breed)
by: Danica Hasanbašić, et al.
Published: (2007-11-01)

Genotoxic, teratotoxic and oral toxic assessments of Antrodia cinnamomea health food product (Leader Deluxe Antrodia cinnamomea®)
by: Chin-Chung Lin, et al.
Published: (2015-01-01)

The impact of physical activity on the level of chromosome aberrations
by: Šošić Gordana M., et al.
Published: (2015-01-01)

Reproductive and genotoxic effects of dinotefuran in male Sprague Dawley rats
by: A. G. Abdelkader, et al.
Published: (2025-03-01)

The Anti-Genotoxic Activity of Wastewaters Produced after Water-Steam Distillation of Bulgarian <i>Rosa damascena</i> Mill. and <i>Rosa alba</i> L. Essential Oils
by: Svetla Gateva, et al.
Published: (2022-03-01)

Effect of met-enkephalin on chromosomal aberrations in the lymphocytes of the peripheral blood of patients with multiple sclerosis
by: Maida Rakanović-Todić, et al.
Published: (2014-05-01)

Radon concentration and related employees’ chromosome aberration and micronuclei in subways in a city of Zhejiang Province
by: Zhiqiang XUAN, et al.
Published: (2024-09-01)

Evaluation of an Immunomodulator Drug as a Radioprotectant on Human Peripheral Blood Lymphocytes In Vitro
by: Zahra Sattarpour, et al.
Published: (2018-01-01)

Protective Effect of Cafestol on Doxorubicin-induced Genotoxicity in Rats
by: Sara A. Al-Kenany, et al.
Published: (2023-11-01)

Analysis of Delphinidin and Luteolin Genotoxicity in Human Lymphocyte Culture
by: Jasmin Ezić, et al.
Published: (2015-08-01)

The genotoxicity of an aqueous extract of Gyejibokryeong-hwan
by: Mee-Young Lee, et al.
Published: (2018-01-01)

Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocytes
by: André B.S. Figueiredo, et al.
Published: (2004-01-01)

Early occupational exposure to lead on neutrophil-to-lymphocyte ratio and genotoxicity
by: Yu Meng, et al.
Published: (2021-06-01)

Genotoxic changes in peripheral lymphocytes after therapeutic exposure to crude coal tar and ultraviolet radiation
by: Andrea Malkova, et al.
Published: (2016-12-01)

Establishment of ex vivo calibration curve for X-ray induced “dicentric + ring” and micronuclei in human peripheral lymphocytes for biodosimetry during radiological emergencies, and validation with dose blinded samples
by: J. Vijayalakshmi, et al.
Published: (2023-06-01)

Evaluation of micronuclei in tobacco users: A study in Punjabi population
by: Himanta Bansal, et al.
Published: (2012-01-01)

Albizia chinensis bark extract ameliorates the genotoxic effect of cyclophosphamide
by: Marian Nabil, et al.
Published: (2020-09-01)