DKK1 inhibits canonical Wnt signaling in human papillomavirus-positive penile cancer cells

DKK1 inhibits canonical Wnt signaling in human papillomavirus-positive penile cancer cells

Penile squamous cell cancer (PSCC) is the most frequent penile malignant disease. Infections with human papillomaviruses (HPV) are a major etiologic driver of PSCC. However, the molecular details of the underlying carcinogenesis are understudied because of rare clinical specimens and missing cell li...

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Bibliographic Details
Main Authors: Isabelle Ariane Bley, Anabel Zwick, Muriel Charlotte Hans, Katrin Thieser, Viktoria Wagner, Nicole Ludwig, Oybek Khalmurzaev, Vsevolod Borisovich Matveev, Philine Loertzer, Alexey Pryalukhin, Arndt Hartmann, Carol-Immanuel Geppert, Hagen Loertzer, Heiko Wunderlich, Carsten Maik Naumann, Holger Kalthoff, Kerstin Junker, Sigrun Smola, Stefan Lohse
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Translational Oncology
Subjects:
β-catenin
Dickkopf1
HPV
Penile cancer
Wnt pathway
Stemness
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523321002588

Internet

http://www.sciencedirect.com/science/article/pii/S1936523321002588

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