HIV-1 Diversity in the Envelope Glycoproteins: Implications for Viral Entry Inhibition

Entry of HIV-1 into a host cell is a multi-step process, with the viral envelope gp120 and gp41 acting sequentially to mediate the viral attachment, CD4 binding, coreceptor binding, and fusion of the viral and host membranes. The emerging class of antiretroviral agents, collectively known as entry i...

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Bibliographic Details
Main Authors: Sabrina E. M. Almeida, Leonardo Augusto Luvison Araújo
Format: Article
Language:English
Published: MDPI AG 2013-02-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/5/2/595