Population Pharmacokinetics and Dosing Optimization of Vancomycin in Pediatric Liver Transplant Recipients

Population Pharmacokinetics and Dosing Optimization of Vancomycin in Pediatric Liver Transplant Recipients

ABSTRACT Methicillin-resistant Staphylococcus aureus infections are a significant cause of morbidity and mortality in pediatric liver transplant (LT) recipients. Physiological changes following LT may affect vancomycin pharmacokinetics; however, appropriate dosing to achieve sufficient drug exposure...

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Bibliographic Details
Main Authors: Kensuke Shoji, Jumpei Saito, Hidenori Nakagawa, Takanori Funaki, Akinari Fukuda, Seisuke Sakamoto, Mureo Kasahara, Jeremiah D. Momper, Edmund V. Capparelli, Isao Miyairi
Format: Article
Language:English
Published: American Society for Microbiology 2021-10-01
Series:Microbiology Spectrum
Subjects:
vancomycin
children
liver transplantation
population pharmacokinetics
Online Access:https://journals.asm.org/doi/10.1128/Spectrum.00460-21

Internet

https://journals.asm.org/doi/10.1128/Spectrum.00460-21

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