On the use of multiple imputation to address data missing by design as well as unintended missing data in case-cohort studies with a binary endpoint

Abstract Background Case-cohort studies are conducted within cohort studies, with the defining feature that collection of exposure data is limited to a subset of the cohort, leading to a large proportion of missing data by design. Standard analysis uses inverse probability weighting (IPW) to address...

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Bibliographic Details
Main Authors: Melissa Middleton, Cattram Nguyen, John B. Carlin, Margarita Moreno-Betancur, Katherine J. Lee
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:https://doi.org/10.1186/s12874-023-02090-5