Protocol for infecting and monitoring susceptible k18-hACE2 mice with SARS-CoV-2
Summary: Intranasal infection of k18-hACE2 mice with SARS-CoV-2 recapitulates the clinical characteristics present in severe COVID-19. Here, we present a protocol for intranasal administration of SARS-CoV-2 to k18-hACE2 mice and their subsequent daily monitoring. We describe steps for intranasal ino...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-06-01
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Series: | STAR Protocols |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666166723002708 |