TWEAK Signaling‐Induced ID1 Expression Drives Malignant Transformation of Hepatic Progenitor Cells During Hepatocarcinogenesis

TWEAK Signaling‐Induced ID1 Expression Drives Malignant Transformation of Hepatic Progenitor Cells During Hepatocarcinogenesis

Abstract The malignant transformation of hepatic progenitor cells (HPCs) in the inflammatory microenvironment is the root cause of hepatocarcinogenesis. However, the potential molecular mechanisms are still elusive. The HPCs subgroup is identified by single‐cell RNA (scRNA) sequencing and the phenot...

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Bibliographic Details
Main Authors: Wenting Liu, Lu Gao, Xiaojuan Hou, Shiyao Feng, Haixin Yan, Hongyu Pan, Shichao Zhang, Xue Yang, Jinghua Jiang, Fei Ye, Qiudong Zhao, Lixin Wei, Zhipeng Han
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Advanced Science
Subjects:
hepatic progenitor cells
inflammatory microenvironment
inhibitor of differentiation‐1
single‐cell RNA sequencing
tumor necrosis factor‐like weak inducer of apoptosis (TWEAK)
Online Access:https://doi.org/10.1002/advs.202300350

Internet

https://doi.org/10.1002/advs.202300350

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