From α-Bromomethylbutenolide to Fused Tri(Tetra) Cyclic Dihydrofurandiones through Barbier Reaction–Heck Arylation Sequence

From α-Bromomethylbutenolide to Fused Tri(Tetra) Cyclic Dihydrofurandiones through Barbier Reaction–Heck Arylation Sequence

A Barbier reaction–Heck arylation sequence from α-bromomethylbutenolide to fused tri and tetracyclic lactones has been developed. The first step involving a Barbier reaction enabled installing ortho-bromoaromatics in α-ylidene γ-lactones. The latter substrates were subjected to intramolecular Heck r...

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Bibliographic Details
Main Authors: Arbia Talbi, Anne Gaucher, Flavien Bourdreux, Jérôme Marrot, Mohamed L. Efrit, Hédi M’Rabet, Damien Prim
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Molecules
Subjects:
bromomethylbutenolide
tri(tetra)cyclic architectures
Barbier
intramolecular Heck reaction
Online Access:https://www.mdpi.com/1420-3049/22/12/2171

Internet

https://www.mdpi.com/1420-3049/22/12/2171

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