CFTR Modulation Reduces SARS-CoV-2 Infection in Human Bronchial Epithelial Cells

CFTR Modulation Reduces SARS-CoV-2 Infection in Human Bronchial Epithelial Cells

People with cystic fibrosis should be considered at increased risk of developing severe symptoms of COVID-19. Strikingly, a broad array of evidence shows reduced spread of SARS-CoV-2 in these subjects, suggesting a potential role for CFTR in the regulation of SARS-CoV-2 infection/replication. Here,...

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Bibliographic Details
Main Authors: Virginia Lotti, Flavia Merigo, Anna Lagni, Andrea Di Clemente, Marco Ligozzi, Paolo Bernardi, Giada Rossini, Ercole Concia, Roberto Plebani, Mario Romano, Andrea Sbarbati, Claudio Sorio, Davide Gibellini
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cells
Subjects:
SARS-CoV-2 virus
cystic fibrosis
CFTR
ACE-2
CFTR inhibitor
human bronchial epithelial cells
Online Access:https://www.mdpi.com/2073-4409/11/8/1347

Internet

https://www.mdpi.com/2073-4409/11/8/1347

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