Four Pathways Involving Innate Immunity in the Pathogenesis of Preeclampsia

The maternal innate immune system plays an important role both in normal pregnancy as well as hypertensive disorders of pregnancy including preeclampsia (PE). We propose 4 pathways that involve excessive innate immunity that lead to most forms of PE. Pre-existing endothelial dysfunction plus pregn...

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Bibliographic Details
Main Authors: Kelsey R Bounds, M. Karen Newell-Rogers, Brett M Mitchell
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcvm.2015.00020/full