Four Pathways Involving Innate Immunity in the Pathogenesis of Preeclampsia
The maternal innate immune system plays an important role both in normal pregnancy as well as hypertensive disorders of pregnancy including preeclampsia (PE). We propose 4 pathways that involve excessive innate immunity that lead to most forms of PE. Pre-existing endothelial dysfunction plus pregn...
Main Authors: | Kelsey R Bounds, M. Karen Newell-Rogers, Brett M Mitchell |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-04-01
|
Series: | Frontiers in Cardiovascular Medicine |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fcvm.2015.00020/full |
Similar Items
-
Expression of placental growth factor mRNA in preeclampsia
by: Pooneh Nikuei, et al.
Published: (2017-05-01) -
Dysregulation of Complement Activation and Placental Dysfunction: A Potential Target to Treat Preeclampsia?
by: E. Pierik, et al.
Published: (2020-01-01) -
REALITIES AND PROSPECTS FOR PHARMACOLOGICAL CORRECTION OF «ADMA-ENOS"-ASSOCIATED WAYS IN PREECLAMPSIA
by: M. V. Pokrovsky, et al.
Published: (2016-01-01) -
Neutrophil extracellular traps: molecular and cellular mechanisms of formation, role in the development of placental disorders and preeclampsia
by: Susanna A. Gasparyan, et al.
Published: (2023-12-01) -
Sustained Elevated Circulating Activin A Impairs Global Longitudinal Strain in Pregnant Rats: A Potential Mechanism for Preeclampsia-Related Cardiac Dysfunction
by: Bhavisha A. Bakrania, et al.
Published: (2022-02-01)