Parvifloron D-based potential therapy for glioblastoma: Inducing apoptosis via the mitochondria dependent pathway

Parvifloron D-based potential therapy for glioblastoma: Inducing apoptosis via the mitochondria dependent pathway

Glioblastoma (GB) is the most malignant and frequent primary tumor of the central nervous system. The lack of diagnostic tools and the poor prognosis associated with this tumor type leads to restricted and limited options of treatment, namely surgical resection and radio-chemotherapy. However, despi...

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Bibliographic Details
Main Authors: Mariana Magalhães, Eva María Domínguez-Martín, Joana Jorge, Ana Cristina Gonçalves, Ana María Díaz-Lanza, Bruno Manadas, Thomas Efferth, Patrícia Rijo, Célia Cabral
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
glioblastoma
Plectranthus spp.
abietane diterpenes
antitumor activity
molecular mechanisms
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1006832/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.1006832/full

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