Degeneration of Aortic Valves in a Bioreactor System with Pulsatile Flow

Degeneration of Aortic Valves in a Bioreactor System with Pulsatile Flow

Calcific aortic valve disease is the most common valvular heart disease in industrialized countries. Pulsatile pressure, sheer and bending stress promote initiation and progression of aortic valve degeneration. The aim of this work is to establish an ex vivo model to study the therein involved proce...

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Bibliographic Details
Main Authors: Naima Niazy, Mareike Barth, Jessica I. Selig, Sabine Feichtner, Babak Shakiba, Asya Candan, Alexander Albert, Karlheinz Preuß, Artur Lichtenberg, Payam Akhyari
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomedicines
Subjects:
calcific aortic valve disease
degeneration
bioreactor system
tissue cultivation
ECM remodeling
Online Access:https://www.mdpi.com/2227-9059/9/5/462

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https://www.mdpi.com/2227-9059/9/5/462

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