Notopterol Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension in Rat

Notopterol Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension in Rat

IntroductionCurrent targeted pulmonary arterial hypertension (PAH) therapies have improved lung hemodynamics, cardiac function, and quality of life; however, none of these have reversed the ongoing remodeling of blood vessels. Considering notopterol, a linear furocoumarin extracted from the root of...

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Bibliographic Details
Main Authors: Lin Huang, Huayang Li, Suiqing Huang, Shunjun Wang, Quan Liu, Li Luo, Shuangjiao Gan, Guangguo Fu, PeiYun Zou, Guangxian Chen, Zhongkai Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
pulmonary arterial hypertension
notopterol
pulmonary vascular remodeling
inflammation
pulmonary arterial smooth muscular cell
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.859422/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.859422/full

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