Bioavailable central nervous system disease-modifying therapies for multiple sclerosis

Disease-modifying therapies for relapsing multiple sclerosis reduce relapse rates by suppressing peripheral immune cells but have limited efficacy in progressive forms of the disease where cells in the central nervous system play a critical role. To our knowledge, alemtuzumab, fumarates (dimethyl, d...

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Bibliographic Details
Main Authors: Hans-Peter Hartung, Bruce A.C. Cree, Michael Barnett, Sven G. Meuth, Amit Bar-Or, Lawrence Steinman
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1290666/full