CD38 Drives Progress of Osteoarthritis by Affecting Cartilage Homeostasis

Objective To observe expression of CD38, a key modulator of nicotinamide dinucleotide (NAD+) metabolism in mice with knee osteoarthritis, and protective effect of CD38 inhibition during the osteoarthritis (OA) development. Method The destabilization of the medial meniscus (DMM) model was performed i...

Full description

Bibliographic Details
Main Authors: Jin‐jin Ma, Jun Ying, Jin‐yu Wang, Tao‐tao Xu, Han‐ting Xia, Hong‐ting Jin, Lu‐wei Xiao, Wen‐jun Shang, Wei‐qian Wang, Jian‐yin Feng
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:Orthopaedic Surgery
Subjects:
Online Access:https://doi.org/10.1111/os.13258