CD38 Drives Progress of Osteoarthritis by Affecting Cartilage Homeostasis
Objective To observe expression of CD38, a key modulator of nicotinamide dinucleotide (NAD+) metabolism in mice with knee osteoarthritis, and protective effect of CD38 inhibition during the osteoarthritis (OA) development. Method The destabilization of the medial meniscus (DMM) model was performed i...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-05-01
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Series: | Orthopaedic Surgery |
Subjects: | |
Online Access: | https://doi.org/10.1111/os.13258 |