Spt6 levels are modulated by PAAF1 and proteasome to regulate the HIV-1 LTR

Spt6 levels are modulated by PAAF1 and proteasome to regulate the HIV-1 LTR

<p>Abstract</p> <p>Background</p> <p>Tat-mediated activation of the HIV-1 promoter depends upon a proteasome-associated factor, PAAF1, which dissociates 26S proteasome to produce 19S RP that is essential for transcriptional elongation. The effect of PAAF1 on proteasome...

Full description

Bibliographic Details
Main Authors: Nakamura Mirai, Basavarajaiah Poornima, Rousset Emilie, Beraud Cyprien, Latreille Daniel, Henaoui Imène-Sarah, Lassot Irina, Mari Bernard, Kiernan Rosemary
Format: Article
Language:English
Published: BMC 2012-02-01
Series:Retrovirology
Subjects:
LTR
transcription
Tat
Spt6
PAAF1
proteasome
Online Access:http://www.retrovirology.com/content/9/1/13

Internet

http://www.retrovirology.com/content/9/1/13

Similar Items