Evaluation of a quantitative real-time PCR assay to measure HIV-specific mucosal CD8+ T cell responses in the cervix.

Evaluation of a quantitative real-time PCR assay to measure HIV-specific mucosal CD8+ T cell responses in the cervix.

Several candidate HIV vaccines aim to induce virus-specific cellular immunity particularly in the genital tract, typically the initial site of HIV acquisition. However, standardized and sensitive methods for evaluating HIV-specific immune responses at the genital level are lacking. Therefore we eval...

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Bibliographic Details
Main Authors: Duncan Chege, Yijie Chai, Sanja Huibner, Lyle McKinnon, Charles Wachihi, Makubo Kimani, Walter Jaoko, Joshua Kimani, T Blake Ball, Francis A Plummer, Rupert Kaul, Anuradha Rebbapragada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2951338?pdf=render

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http://europepmc.org/articles/PMC2951338?pdf=render

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