MiR-34a expression has an effect for lower risk of metastasis and associates with expression patterns predicting clinical outcome in breast cancer.

MiR-34a acts as a candidate tumour suppressor gene, and its expression is reduced in several cancer types. We aimed to study miR-34a expression in breast cancer and its correlation with tumour characteristics and clinical outcome, and regulatory links with other genes. We analysed miR-34a expression...

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Main Authors: Hanna Peurala, Dario Greco, Tuomas Heikkinen, Sippy Kaur, Jirina Bartkova, Maral Jamshidi, Kristiina Aittomäki, Päivi Heikkilä, Jiri Bartek, Carl Blomqvist, Ralf Bützow, Heli Nevanlinna
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3213093?pdf=render