MiR-34a expression has an effect for lower risk of metastasis and associates with expression patterns predicting clinical outcome in breast cancer.
MiR-34a acts as a candidate tumour suppressor gene, and its expression is reduced in several cancer types. We aimed to study miR-34a expression in breast cancer and its correlation with tumour characteristics and clinical outcome, and regulatory links with other genes. We analysed miR-34a expression...
Main Authors: | Hanna Peurala, Dario Greco, Tuomas Heikkinen, Sippy Kaur, Jirina Bartkova, Maral Jamshidi, Kristiina Aittomäki, Päivi Heikkilä, Jiri Bartek, Carl Blomqvist, Ralf Bützow, Heli Nevanlinna |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3213093?pdf=render |
Similar Items
-
High miR-30 Expression Associates with Improved Breast Cancer Patient Survival and Treatment Outcome
by: Maral Jamshidi, et al.
Published: (2021-06-01) -
Markers associated with genomic instability, immunogenicity and immune therapy responsiveness in Metaplastic carcinoma of the breast: Expression of γH2AX, pRPA2, P53, PD-L1 and tumor infiltrating lymphocytes in 76 cases
by: S. Voutilainen, et al.
Published: (2022-12-01) -
Comprehensive analysis of <it>NuMA </it>variation in breast cancer
by: Aittomäki Kristiina, et al.
Published: (2008-03-01) -
Pathogenic Variant Spectrum in Breast Cancer Risk Genes in Finnish Patients
by: Anna K. Nurmi, et al.
Published: (2022-12-01) -
CHEK2 c.1100delC mutation is associated with an increased risk for male breast cancer in Finnish patient population
by: Sanna Hallamies, et al.
Published: (2017-09-01)