Combined analyses of RNA-sequence and Hi-C along with GWAS loci—A novel approach to dissect keloid disorder genetic mechanism

Combined analyses of RNA-sequence and Hi-C along with GWAS loci—A novel approach to dissect keloid disorder genetic mechanism

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Keloid disorder is a tumour-like disease with invasive growth and a high recurrence rate. Genetic contribution is well expected due to the presence of autosomal dominant inheritance and various genetic mutations in keloid lesions. However, GWAS failed to reveal functional variants in exon regions bu...

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Bibliographic Details
Main Authors: Jia Huang, Xiaobo Zhou, Wenbo Wang, Guangdong Zhou, WenJie Zhang, Zhen Gao, Xiaoli Wu, Wei Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-06-01
Series:PLoS Genetics
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202908/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202908/?tool=EBI

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