Use of Integrase-Minus Lentiviral Vector for Transient Expression

Objective: Lentivirus-derived vectors are among the most promising viral vectors for gene therapy which is currently available, but their use in clinical practice is limited due to associated risk of insertional mutagenesis. Gene targeting is an ideal method for gene therapy, but it has low efficien...

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Bibliographic Details
Main Authors: Hossein Azadeh, Nader Mansour Samaei, Ghasem Janbabai, Mohammad Reza Haghshenas, Hossein Khanahmad Shahreza, Touraj Farazmandfar
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2012-01-01
Series:Cell Journal
Subjects:
Online Access:http://celljournal.org/library/upload/article/af_4233332227332425422463677633232474822732farazmandfar.pdf