The role of DNA polymerase I in tolerating single-strand breaks generated at clustered DNA damage in Escherichia coli
Abstract Clustered DNA damage, when multiple lesions are generated in close proximity, has various biological consequences, including cell death, chromosome aberrations, and mutations. It is generally perceived as a hallmark of ionizing radiation. The enhanced mutagenic potential of lesions within a...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2024-08-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-024-69823-4 |