Impact of Critical Material Attributes of HPMC on the Release of Gliclazide from Hydrophilic Matrix Tablets
The influence of HPMC viscosity and the degree of substitution hydroxypropyl level (DSHP) on the release rate of gliclazide was examined. The increase in the HPMC viscosity led to a significant decrease in the release rate. The second parameter, DSHP, showed a surprisingly high impact on the release...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
University of Huddersfield Press
2022-11-01
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| Series: | British Journal of Pharmacy |
| Subjects: | |
| Online Access: | https://www.bjpharm.org.uk/article/id/1244/ |