Unravelling the Proteomics of HLA-B*57:01<sup>+</sup> Antigen Presenting Cells during Abacavir Medication

Unravelling the Proteomics of HLA-B*57:01<sup>+</sup> Antigen Presenting Cells during Abacavir Medication

Type B adverse drug reactions (ADRs) are unpredictable based on the drug’s pharmacology and represent a key challenge in pharmacovigilance. For human leukocyte antigen (HLA)-mediated type B ADRs, it is assumed that the protein/small-molecule interaction alters the biophysical and mechanistic propert...

Full description

Bibliographic Details
Main Authors: Funmilola Josephine Haukamp, Eline Gall, Gia-Gia Toni Hò, Wiebke Hiemisch, Florian Stieglitz, Joachim Kuhn, Rainer Blasczyk, Andreas Pich, Christina Bade-Döding
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Journal of Personalized Medicine
Subjects:
adverse drug reaction
HLA-B*57:01
abacavir
proteome
hypersensitivity
Online Access:https://www.mdpi.com/2075-4426/12/1/40

Internet

https://www.mdpi.com/2075-4426/12/1/40

Similar Items