Absolute Quantification of Donor-Derived Cell-Free DNA in Pediatric and Adult Patients After Heart Transplantation: A Prospective Study

Absolute Quantification of Donor-Derived Cell-Free DNA in Pediatric and Adult Patients After Heart Transplantation: A Prospective Study

In this prospective study we investigated a cohort after heart transplantation with a novel PCR-based approach with focus on treated rejection. Blood samples were collected coincidentally to biopsies, and both absolute levels of dd-cfDNA and donor fraction were reported using digital PCR. 52 patient...

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Bibliographic Details
Main Authors: Jens Böhmer, Carina Wasslavik, Daniel Andersson, Anders Ståhlberg, Marianne Jonsson, Håkan Wåhlander, Kristjan Karason, Jan Sunnegårdh, Staffan Nilsson, Julia Asp, Göran Dellgren, Anne Ricksten
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Transplant International
Subjects:
heart transplantation
rejection
prospective follow-up
cell free DNA
surveillance
Online Access:https://www.frontierspartnerships.org/articles/10.3389/ti.2023.11260/full

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https://www.frontierspartnerships.org/articles/10.3389/ti.2023.11260/full

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