4-(Phenylselanyl)-2H-chromen-2-one-Loaded Nanocapsule Suspension—A Promising Breakthrough in Pain Management: Comprehensive Molecular Docking, Formulation Design, and Toxicological and Pharmacological Assessments in Mice

4-(Phenylselanyl)-2H-chromen-2-one-Loaded Nanocapsule Suspension—A Promising Breakthrough in Pain Management: Comprehensive Molecular Docking, Formulation Design, and Toxicological and Pharmacological Assessments in Mice

Therapies for the treatment of pain and inflammation continue to pose a global challenge, emphasizing the significant impact of pain on patients’ quality of life. Therefore, this study aimed to investigate the effects of 4-(Phenylselanyl)-2H-chromen-2-one (4-PSCO) on pain-associated proteins through...

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Bibliographic Details
Main Authors: Caren Aline Ramson da Fonseca, Vinicius Costa Prado, Jaini Janke Paltian, Jean Carlo Kazmierczak, Ricardo Frederico Schumacher, Marcel Henrique Marcondes Sari, Larissa Marafiga Cordeiro, Aline Franzen da Silva, Felix Alexandre Antunes Soares, Robson da Silva Oliboni, Cristiane Luchese, Letícia Cruz, Ethel Antunes Wilhelm
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Pharmaceutics
Subjects:
nanotechnology
pain
<i>Caenorhabditis elegans</i>
mice
organoselenium
coumarin
Online Access:https://www.mdpi.com/1999-4923/16/2/269

Internet

https://www.mdpi.com/1999-4923/16/2/269

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