3′-Aminothiocyclohexanespiro-5′-hydantoin and Its Pt(II) Complex—Synthesis, Cytotoxicity and Xanthine Oxidase Inhibitory Activity

3′-Aminothiocyclohexanespiro-5′-hydantoin and Its Pt(II) Complex—Synthesis, Cytotoxicity and Xanthine Oxidase Inhibitory Activity

Herein, we report the synthesis of platinum(II) complex bearing 3′-aminothiocyclohexanespiro-5′-hydantoin as ligand. The complex was characterized by IR, NMR spectral analyses, elemental analyses and density functional theory (DFT) calculations. Cytotoxicity and inhibitory potential on xanthine oxid...

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Bibliographic Details
Main Authors: Emiliya Cherneva, Mariyana Atanasova, Žaklina Šmelcerović, Katarina Tomović, Rossen Buyukliev, Andrija Šmelcerović, Adriana Bakalova
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Inorganics
Subjects:
platinum complexes
hydantoin
cytotoxicity
xanthine oxidase inhibition
Online Access:https://www.mdpi.com/2304-6740/10/10/175

Internet

https://www.mdpi.com/2304-6740/10/10/175

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