Patterns of selection in anti-malarial immune genes in malaria vectors: evidence for adaptive evolution in LRIM1 in Anopheles arabiensis.

Co-evolution between Plasmodium species and its vectors may result in adaptive changes in genes that are crucial components of the vector's defense against the pathogen. By analyzing which genes show evidence of positive selection in malaria vectors, but not in closely related non-vectors, we c...

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Bibliographic Details
Main Authors: Michel A Slotman, Aristeidis Parmakelis, Jonathon C Marshall, Parfait H Awono-Ambene, Christophe Antonio-Nkondjo, Frederic Simard, Adalgisa Caccone, Jeffrey R Powell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1945087?pdf=render