2-Hydroxypropyl-β-Cyclodextrin Acts as a Novel Anticancer Agent.

2-Hydroxypropyl-β-cyclodextrin (HP-β-CyD) is a cyclic oligosaccharide that is widely used as an enabling excipient in pharmaceutical formulations, but also as a cholesterol modifier. HP-β-CyD has recently been approved for the treatment of Niemann-Pick Type C disease, a lysosomal lipid storage disor...

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Bibliographic Details
Main Authors: Masako Yokoo, Yasushi Kubota, Keiichi Motoyama, Taishi Higashi, Masatoshi Taniyoshi, Hiroko Tokumaru, Rena Nishiyama, Yoko Tabe, Sakiko Mochinaga, Akemi Sato, Naoko Sueoka-Aragane, Eisaburo Sueoka, Hidetoshi Arima, Tetsumi Irie, Shinya Kimura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4633159?pdf=render