Continuous-flow catalytic asymmetric hydrogenations: Reaction optimization using FTIR inline analysis

Continuous-flow catalytic asymmetric hydrogenations: Reaction optimization using FTIR inline analysis

The asymmetric organocatalytic hydrogenation of benzoxazines, quinolines, quinoxalines and 3H-indoles in continuous-flow microreactors has been developed. Reaction monitoring was achieved by using an inline ReactIR flow cell, which allows fast and convenient optimization of reaction parameters. The...

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Bibliographic Details
Main Authors: Magnus Rueping, Teerawut Bootwicha, Erli Sugiono
Format: Article
Language:English
Published: Beilstein-Institut 2012-02-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
asymmetric reduction
binolphosphoric acid
Brønsted acid
Hantzsch dihydropyridine
IR spectroscopy
real-time analysis
Online Access:https://doi.org/10.3762/bjoc.8.32

Internet

https://doi.org/10.3762/bjoc.8.32

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