Tetrahydroxystilbene Glucoside Protects Against Oxidized LDL-Induced Endothelial Dysfunction via Regulating Vimentin Cytoskeleton and its Colocalization with ICAM-1 and VCAM-1

Tetrahydroxystilbene Glucoside Protects Against Oxidized LDL-Induced Endothelial Dysfunction via Regulating Vimentin Cytoskeleton and its Colocalization with ICAM-1 and VCAM-1

Background: Endothelial cell dysfunction triggered by oxidized low-density lipoprotein (oxLDL) is the main event occurring during the development of atherosclerosis. 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (TSG), an active component of the rhizome extract from Polygonum multiflorum, exh...

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Bibliographic Details
Main Authors: Wenjuan Yao, Chao Huang, Qinju Sun, Xiang Jing, Huiming Wang, Wei Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
Tetrahydroxystilbene glucoside
Oxidized LDL
Endothelial dysfunction
Vimentin
Online Access:http://www.karger.com/Article/FullText/366349

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http://www.karger.com/Article/FullText/366349

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