The temporal profile of activity-dependent presynaptic phospho-signalling reveals long-lasting patterns of poststimulus regulation.

The temporal profile of activity-dependent presynaptic phospho-signalling reveals long-lasting patterns of poststimulus regulation.

Depolarization of presynaptic terminals stimulates calcium influx, which evokes neurotransmitter release and activates phosphorylation-based signalling. Here, we present the first global temporal profile of presynaptic activity-dependent phospho-signalling, which includes two KCl stimulation levels...

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Bibliographic Details
Main Authors: Kasper Engholm-Keller, Ashley J Waardenberg, Johannes A Müller, Jesse R Wark, Rowena N Fernando, Jonathan W Arthur, Phillip J Robinson, Dirk Dietrich, Susanne Schoch, Mark E Graham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-03-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000170

Internet

https://doi.org/10.1371/journal.pbio.3000170

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