Cardiac Glycosides Increase Temozolomide Anticancer Activity in Therapy Resistant Glioblastoma Cells

Cardiac Glycosides Increase Temozolomide Anticancer Activity in Therapy Resistant Glioblastoma Cells

Glioblastomas (GBMs) are a form of malignant gliomas characterized by a dismal prognosis. Standard treatment for glioblastoma patients is combined maximal surgical removal of the tumor with postoperative radiotherapy and concomitant chemotherapy with Temozolomide (TMZ). Among the histological charac...

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Bibliographic Details
Main Authors: Anisha Valluri, Logan Lawrence, Krista L. Denning, Jonathan Cuda, Guo-Zhang Zhu
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Translational Medicine
Subjects:
glioblastoma
anticancer activity
cardiac glycosides
combination therapy
digoxin
sodium/potassium pump
Online Access:https://www.mdpi.com/2673-8937/2/2/12

Internet

https://www.mdpi.com/2673-8937/2/2/12

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