Investigation of Molecular Features Involved in Clinical Responses and Survival in Advanced Endometrial Carcinoma Treated by Hormone Therapy

Investigation of Molecular Features Involved in Clinical Responses and Survival in Advanced Endometrial Carcinoma Treated by Hormone Therapy

Hormone therapy (HT) is an effective treatment for metastatic endometrial carcinoma (mEC), with limited toxicity and low cost. We focused on molecular analysis of mECs treated by HT and, for the first time to date, we compared the genomic profiles of paired metastasis and primary ECs. The main objec...

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Bibliographic Details
Main Authors: Mathias Neron, Arnaud Guille, Lucie Allegre, Pierre-Emmanuel Colombo, Cristina Leaha, José Adelaide, Nadine Carbuccia, Frédéric Courtier, Florence Boissiere, Evelyne Crapez, Michel Fabbro, Sébastien Gouy, Emilie Mamessier, Éric Lambaudie, Daniel Birnbaum, François Bertucci, Max Chaffanet
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Journal of Personalized Medicine
Subjects:
metastatic endometrial carcinoma
hormone therapy
predictive factors
mutations
copy number alterations
protein expression
Online Access:https://www.mdpi.com/2075-4426/12/5/655

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https://www.mdpi.com/2075-4426/12/5/655

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