The Immunomodulatory Capacity of an Epstein-Barr Virus Abortive Lytic Cycle: Potential Contribution to Viral Tumorigenesis

The Immunomodulatory Capacity of an Epstein-Barr Virus Abortive Lytic Cycle: Potential Contribution to Viral Tumorigenesis

Epstein-Barr virus (EBV) is characterized by a bipartite life cycle in which latent and lytic stages are alternated. Latency is compatible with long-lasting persistency within the infected host, while lytic expression, preferentially found in oropharyngeal epithelial tissue, is thought to favor host...

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Bibliographic Details
Main Authors: Abigail Morales-Sánchez, Ezequiel M. Fuentes-Panana
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Cancers
Subjects:
EBV
KSHV
HCMV
abortive lytic cycle
immunomodulation
tumorigenesis
autocrine/paracrine signaling
oncomodulation
Online Access:http://www.mdpi.com/2072-6694/10/4/98

Internet

http://www.mdpi.com/2072-6694/10/4/98

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