NTRK fusion positive colorectal cancer is a unique subset of CRC with high TMB and microsatellite instability

Abstract TRK fusions are rare but targetable mutations which occur across a wide variety of cancer types. We report the prevalence of approximately 0.7% for NTRK‐positive colorectal cancer (CRC) by genetically profiling 2519 colonic and rectal tumors. The aberrations of APC and TP53 frequently co‐oc...

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Bibliographic Details
Main Authors: Hui Wang, Zhi‐Wei Li, Qiuxiang Ou, Xue Wu, Misako Nagasaka, Yang Shao, Sai‐Hong Ignatius Ou, Yu Yang
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.4561