T cell receptor convergence is an indicator of antigen-specific T cell response in cancer immunotherapies
T cells are potent at eliminating pathogens and playing a crucial role in the adaptive immune response. T cell receptor (TCR) convergence describes T cells that share identical TCRs with the same amino acid sequences but have different DNA sequences due to codon degeneracy. We conducted a systematic...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2022-11-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/81952 |