T cell receptor convergence is an indicator of antigen-specific T cell response in cancer immunotherapies

T cell receptor convergence is an indicator of antigen-specific T cell response in cancer immunotherapies

T cells are potent at eliminating pathogens and playing a crucial role in the adaptive immune response. T cell receptor (TCR) convergence describes T cells that share identical TCRs with the same amino acid sequences but have different DNA sequences due to codon degeneracy. We conducted a systematic...

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Bibliographic Details
Main Authors:	Mingyao Pan, Bo Li
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2022-11-01
Series:	eLife
Subjects:	TCR repertoire TCR convergence immunotherapy prognosis
Online Access:	https://elifesciences.org/articles/81952

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