Structural and Functional Analysis of SsaV Cytoplasmic Domain and Variable Linker States in the Context of the InvA-SsaV Chimeric Protein

Structural and Functional Analysis of SsaV Cytoplasmic Domain and Variable Linker States in the Context of the InvA-SsaV Chimeric Protein

ABSTRACT The type III secretion (T3S) injectisome is a syringe-like protein-delivery nanomachine widely utilized by Gram-negative bacteria. It can deliver effector proteins directly from bacteria into eukaryotic host cells, which is crucial for the bacterial–host interaction. Intracellular pathogen...

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Bibliographic Details
Main Authors: Jinghua Xu, Jiuqing Wang, Aijun Liu, Yanqing Zhang, Xiang Gao
Format: Article
Language:English
Published: American Society for Microbiology 2021-12-01
Series:Microbiology Spectrum
Subjects:
Salmonella
type III secretion system
injectisome
export gate protein
cryo-EM
Online Access:https://journals.asm.org/doi/10.1128/Spectrum.01251-21

Internet

https://journals.asm.org/doi/10.1128/Spectrum.01251-21

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