Methotrexate-induced toxicities in children with malignancy: a systematic review and meta-analysis

Objective: Methotrexate (MTX) is an anticancer and anti-inflammatory drug widely used to treat various diseases. Some patients are more susceptible to toxicity, some show resistance to chemotherapy. The most conducted studies have investigated the effect of gene polymorphism on MTX toxicity, and lit...

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Bibliographic Details
Main Authors: S. Gharibi, A. Alizadeh, A. Saki Malehi, F. Rahim
Format: Article
Language:English
Published: Verduci Editore 2021-07-01
Series:World Cancer Research Journal
Subjects:
Online Access:https://www.wcrj.net/wp-content/uploads/sites/5/2022/03/e2041.pdf