Hypoxic Cell-Derived Extracellular Vesicles Aggravate Rectal Injury Following Radiotherapy via MiR-122-5p

Hypoxic Cell-Derived Extracellular Vesicles Aggravate Rectal Injury Following Radiotherapy via MiR-122-5p

Radiation-induced rectal injury is a common side effect of radiotherapy. Hypoxia often occurs after radiotherapy. This study aimed to explore the bystander effect of hypoxia on radiation-induced rectal injury. In vivo, apoptosis increased nearby the highly hypoxic area in the rectal tissues in the m...

Full description

Bibliographic Details
Main Authors: Yiqing Xu, Yulong Ge, Xuming Chen, Yingzi Zhang, Huanliang Chen, Dongli Liu, Yue Lu, Yong Liu, Wenzhi Tu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
rectal injury
hypoxia
extracellular vesicle
apoptosis
miR-122-5p
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.892575/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.892575/full

Similar Items