Dysregulation of ferroptosis-related genes in granulosa cells associates with impaired oocyte quality in polycystic ovary syndrome

Dysregulation of ferroptosis-related genes in granulosa cells associates with impaired oocyte quality in polycystic ovary syndrome

BackgroundPoor oocyte quality remains one of the major challenges for polycystic ovary syndrome (PCOS) patients during in vitro fertilization (IVF) treatment. Granulosa cells (GCs) in PCOS display altered functions and could cause an unfavorable microenvironment for oocyte growth and maturation. Fer...

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Bibliographic Details
Main Authors: Jialyu Huang, Hancheng Fan, Chenxi Li, Kangping Yang, Chaoyi Xiong, Siyi Xiong, Shenghui Feng, Shen Chen, Bangqi Wang, Yufang Su, Boyun Xu, Haiyan Yang, Ni Wang, Jing Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Endocrinology
Subjects:
polycystic ovary syndrome
ferroptosis
granulosa cell
oocyte quality
in vitro fertilization
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1346842/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2024.1346842/full

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